
TN221BK
Compatible Brother TN221BK Black Toner Cartridge
2,500 pages
Your HL-3180 takes the TN221BK (standard yield), TN221C (standard yield), TN221M (standard yield), TN221Y (standard yield), TN225C (high yield), TN225Y (high yield) and TN225M (high yield). At our price that is about 0.8¢ a page.
The Brother HL-3180 is a mono laser printer in the HL-3100 series, which shares cartridges across 9 models.
It takes two black cartridges that differ only in capacity: the TN221BK at about 2,500 pages and the TN225C at about 2,200. At our prices that is 0.8¢ a page against 1.0¢, so the high-yield cartridge costs less to run unless you print very little.
Brother has stated publicly that its firmware updates do not block third-party cartridges, and the printer counts pages rather than measuring toner, which is why the Replace Toner message can appear before a cartridge is empty.
When you compare prices, compare cost per page rather than the sticker price: a cheaper cartridge with half the rated yield costs more to run. Every cartridge here ships free, is covered by our printer damage protection and can be returned within 90 days, opened or not.

TN221BK
2,500 pages

TN221C
1,400 pages

TN221M
1,400 pages

TN221Y
1,400 pages

TN225C
2,200 pages

TN225Y
2,200 pages

TN225M
2,200 pages
| Cartridge | Yield | Price | Per page |
|---|---|---|---|
| TN221BK | 2,500 pages | $20.99 | 0.8¢ |
| TN221C | 1,400 pages | $18.99 | 1.4¢ |
| TN221M | 1,400 pages | $18.99 | 1.4¢ |
| TN221Y | 1,400 pages | $18.99 | 1.4¢ |
| TN225C High yield | 2,200 pages | $20.99 | 1.0¢ |
| TN225Y High yield | 2,200 pages | $20.99 | 1.0¢ |
| TN225M High yield | 2,200 pages | $20.99 | 1.0¢ |
About $9.66 a month in toner, roughly one TN221BK every 3 months.
The TN221BK, TN221C, TN221M, TN221Y, TN225C, TN225Y and TN225M. Brother lists these cartridges as compatible with this model, and the yields on this page are Brother's published figures.
No. Under the Magnuson-Moss Warranty Act a manufacturer cannot void your warranty because you used a third-party cartridge. If one of ours damages the printer, our printer damage protection covers the repair.
Most of these share the same cartridges. Check the model page to be sure.
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Page updated Sep 22, 2026. Compatibility checked by Dan Whitaker, Print Technician. Brand names and part numbers are used only to identify compatibility. We are not affiliated with or endorsed by any printer manufacturer.